- 基因座控制区[在转基因实验中，其调控作用可使基因表达对整合位点不敏感，而仅仅取决于转基因的拷贝数，如见于珠蛋白基因
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locus control region中文什么意思
百科释义
Locus control regions (LCR) are defined by their ability to enhance the expression of linked genes to physiological levels in a tissue-specific and copy number-dependent manner at ectopic chromatin sites. The concept derives from the idea that developmental and cell lineage-specific regulation of gene expression relies not only on gene-proximal elements such as promoters, enhancers, and silencers, but also on long-range interactions of various cis-regulatory elements and dynamic chromatin alterations.
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